Yes, You Can Open a Wine Bottle With a House Key You've had a hard day and are ready to sit back, relax, and open a bottle of wine, but you can't find a corkscrew. The agony right? You do know that you can open a bottle of wine with a key right? If you don't know how to open a bottle with a key, YouTuber, Dave Hax, is now showing you how to open a wine bottle with an ordinary house key. Just a note, the hack seems to work better on synthetic corks, but try it on a real cork too.